Specifications
- Antibody type:Primary
- Antigen name:ACTR1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:65-160/509
- Form:Liquid
- Gene ID:90
- Antigen synonyms:Activin receptor-like kinase 2|ALK-2|TGFB superfamily receptor type I|ACTRI|ACTR 1|ACVRLK 2|ACTR1|Activin Receptor Type IA|ALK2|ACVR1|Serine/threonine protein kinase receptor R1|Activin A receptor type I|ACVR1A|Activin receptor type-1|Serine/threonine-protein kinase receptor R1|SKR 1|TSR-I|ACTR-I|ALK 2|Hydroxyalkyl protein kinase|ACVR1_HUMAN|ACTR-1|TSRI|FOP|Activin receptor type I|ACVR 1|Activin A receptor type II like kinase 2|SKR1|TGF-B superfamily receptor type I|ACVRLK2
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:55 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human SKR1/ACTR1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a Signalling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion.
Type: Primary
Antigen: ACTR1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 65-160/509
Host: Rabbit
Isotype: IgG
Reactivity: Human