- Antibody type:Primary
- Antigen name:NDST1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:781-882/882
- Form:Liquid
- Gene ID:3340
- Antigen synonyms:HSNST-1|Bunctional heparan sulfate N-deacetylase/N-sulfotransferase 1|N-HSST 1|Heparan sulfate N-deacetylase 1|[Heparan sulfate]-glucosamine N-sulfotransferase 1|NDST-1|HSST1|HSST|Heparan sulfate N-sulfotransferase 1|Glucosaminyl N-deacetylase/N-sulfotransferase 1|N-heparan sulfate sulfotransferase 1|NDST1_HUMAN|HSNST 1|Ndst1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human NDST1
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Essential bifunctional enzyme that catalyses both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
Type: Primary
Antigen: NDST1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 781-882/882
Host: Rabbit
Isotype: IgG
Reactivity: Human