- Antikörper-Typ:Primär
- Antigen-Name:AMPK alpha-1/2 Thr183/Thr172
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 750
- Durchflusszytometrie:Yes
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Reaktivität:Pig,Sheep,Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Gen-ID:5562
- Antigen-Synonyme:PRKAA 1|AI194361|acetyl CoA carboxylase kinase|PRKAA1phospho T172|5' AMP activated protein kinase catalytic subunit alpha 1|AL024255|AMPK 1|Protein kinase AMP activated alpha 1 catalytic subunit|hormone sensitive lipase kinase|cb116|AMPK|HMG CoA reductase kinase|SNF1-like protein AMPK|im:7154392|MGC33776|EC 2.7.11.1|AI450832|C130083N04Rik|AMPKalpha1|MGC57364|kinase AMPK alpha1|AMP -activate kinase alpha 1 subunit|wu:fa94C10|5 AMP activated protein kinase alpha 1catalytic subunit|PRKAA1|AMPK1|AAPK1|AMPKa1|AMPK alpha 1 + AMPK alpha 2 phospho T183/T172|AMPK alpha 1 chain|AMP-activated protein kinase, catalytic, alpha -1|5 AMP activated protein kinase catalytic alpha 1 chain
- Modification:Phosphorylation (Thr172/Thr183)
- Lagerungspuffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:64 kDa
- Lagertemperatur:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Konzentration:1 µg/µl
- Transporttemperatur:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from mouse AMPK alpha 2 around the phosphorylation site of Thr172
- Validierte Anwendungen:ICC
- Reinigung:Purified by Protein A
- Packung:Vial
- VE:100 µl
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Type: Primary
Antigen: AMPK alpha-1/2 Thr183/Thr172
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat; Pig; Sheep