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Anti-AMPK beta 1 Ser108 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-AMPK beta 1 Ser108 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3026R-A750
Supplier:  Bioss
Anti-AMPK beta 1 Ser108 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3026R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    AMPK beta 1 Ser108
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat,
    Mouse
  • Form:
    Liquid
  • Gene ID:
    19079
  • Antigen synonyms:
    protein kinase, AMP-activated, noncatalytic, beta-1|AAKB1_RAT|5 AMP activated protein kinase subunit beta 1|5'-AMP-activated protein kinase subunit beta-1|AMPK subunit beta-1|AMPK beta 1 chain|AMPK|PRKAB1phospho S108|HAMPKb|AMPK beta -1 chain|5'-AMP-activated protein kinase beta-1 subunit|p-AMPK beta 1Ser108|PRKAB1S108|AMP-activated protein kinase beta subunit|AMPK beta 1Ser108|PRKAB1|AMPKb|p-AMPK beta 1S108
  • Modification:
    Phosphorylation (Ser108)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    30 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from mouse AMPK beta 1 around the phosphorylation site of Ser108
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Type: Primary
Antigen: AMPK beta 1 Ser108
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat