Unconjugated

Recombinant

HEK293 cells

Human

–20 °C

Less than 0,1 EU per μg by the LAL method.

Lyophilised from 0,22 μm filtered solution in PBS, pH 7,4, Normally trehalose is added as protectant before Lyophilisation,; Measured by its binding ability in a functional ELISA, Immobilised Human PD-L1, Fc Tag (HPLC-verified) (Cat, No, PD1-H5258) at 10 μg/ml (100 μl/well) can bind Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) with a linear range of 2-40 ng/ml (QC tested),; Measured by its binding ability in a functional ELISA, Immobilised Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) at 2 μg/ml (100 μl/well) can bind Human PD-L2, Fc Tag (Cat, No, PD2-H5251) with a linear range of 0,2-4 ng/ml (Routinely tested),; Measured by its binding ability in a functional ELISA, Immobilised Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) at 2 μg/ml (100 μl/well) can bind Nivolumab with a linear range of 0,1-2 ng/ml (Routinely tested),; Measured by its binding ability in a functional ELISA, Immobilised Human PD-L1, His Tag (HPLC-verified) (Cat, No, PD1-H5229) at series of concentration on MonRabTM Anti-His Tag (C-term) Antibody precoated (0,1 μg/well) plate, can bind Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) at 5 μg/ml (100 μl/well) with a linear range of 10-78 ng/ml (Routinely tested),; Loaded Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) on Protein A Biosensor, can bind Human PD-L1, His Tag (HPLC verified) (Cat, No, PD1-H5229) with an affinity constant of 2,6 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested),; Loaded Human PD-1, Mouse IgG2a Fc Tag (HPLC-verified) (Cat, No, PD1-H5255) on Protein A Biosensor, can bind Human PD-L2, His Tag (SPR verified) (Cat, No, PD2-H5220) with an affinity constant of 0,43 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Q15116-1

Y

Y

Y

CD279|PDCD1|PD1|SLEB2

PD-1

>95%

42,5 kDa

Low

Lyophilised from 0,22 μm filtered solution in PBS, pH 7,4, Normally trehalose is added as protectant before Lyophilisation.

Y

Powder,RT