Anti-CENP-A Mouse Monoclonal Antibody [clone: 42448]
Catalog # ENZOADIKAMCC006E
Supplier: ENZO LIFE SCIENCES
Specifications
- Antibody type:Primary
- Antigen name:Centromere Protein A
- Antigen symbol:CENPA
- Clonality:Monoclonal
- Clone:3-19
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG1
- Reactivity:Human
- Western blot:Yes
- Seq:02
- Form:Liquid
- Antigen synonyms:centromeric protein A|Histone H3 like centromeric protein A.|CENP-A|centromere protein A|Centromere autoantigen A|CENP A|Centromere protein A 17kDa
- Storage buffer:PBS, pH 7,2, containing 50% glycerol
- Storage temperature:–20 °C
- Shipping temperature:Shipped on blue ice
- Immunogen:Synthetic peptide corresponding to a portion of human CENP-A
- Purification:Purified by Protein A affinity chromatography
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Centromere protein A (CENP-A), a 17-19 kDa centromere-specific histone variant, is 62% identical to the carboxy-terminal domain of histone H3. In the presence of DNA, CENP-A forms an octameric complex with histones H4, H2A, and H2B. CENP-A defines active centromere regions by forming centromere-specific nucleosomes on which kinetochores are assembled. CENP-A resides specifically in the inner plate of the kinetochore, and is essential for kinetochore targeting of CENP-C and other kinetochore components. CENP-A is required for nucleosomal packaging of centromeric DNA at interphase.
Type: Primary
Antigen: CENP-A
Clonality: Monoclonal
Clone: 42448
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: