Anti-MDA5 Rabbit Polyclonal Antibody
Catalog # ENZOALX210935C100
Supplier: ENZO LIFE SCIENCES
Specifications
- Antibody type:Primary
- Antigen name:Melanoma Differentiation-Associated protein 5
- Antigen symbol:MDA5
- Clonality:Polyclonal
- Host:Rabbit
- ImmunoPrecipitation:Yes
- Reactivity:Human
- Western blot:Yes
- Seq:02
- Form:Liquid. In PBS containing 0,02% sodium azide.
- Antigen synonyms:Clinically amyopathic dermatomyositis autoantigen 140 kDa|RLR-2|Helicard|Murabutide down-regulated protein|Melanoma differentiation-associated protein 5|RNA helicase-DEAD box protein 116|MDA-5|CADM-140 autoantigen|RIG-I-like receptor 2|Helicase with 2 CARD domains|Interferon-induced with helicase C domain protein 1
- Concentration:1 mg/ml
- Purification:Epitope-affinity purified
- Pk:100 µG
Specifications
About this item
MDA5 is a highly conserved helicase whose ATPase activity can be stimulated by RNA and less potently by DNA. It contains two N-terminal CARD domains and a C-terminal helicase domain. The helicase domain, once freed from the CARD domains, then translocates from the cytoplasm to the nucleus where it acts on chromatin architecture. This could allow a more easy access of CAD, thereby accelerating the degradation of genomic DNA.
- For Immunoprecipitation, Western Blot
Recognizes human MDA5.
Type: Primary
Antigen: MDA5
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human