Specifications
- Pk:50 µG
- Enzyme type:Recombinant
- Species:Mouse
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:CNDP dipeptidase 2
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:53.8 kDa
- Sequence:Met1-Asn475
- Formulation:Supplied as a 0,2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10% Glycerol, pH 8,0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Biological assays
Specifications
About this item
Mouse cytosolic non-specific dipeptidase(CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyses a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyse carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumour suppressor in hepatocellular carcinoma (HCC) cells.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.