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Human recombinant Sentrin-specific protease 2 (from E. coli)
Human recombinant Sentrin-specific protease 2 (from E. coli)
Catalog # PRSI92-222
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Sentrin-specific protease 2 (from E. coli)
Catalog # PRSI92-222
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    N-6 His, SUMO tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Sentrin-specific Protease 2
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    39.2 kD
  • Sequence:
    Asp363-Leu589
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 50 mM HEPES, 5% glycerol pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH₂O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Biological assays

Specifications

About this item

SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyses two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.

Fusion-Tag: N-6 His, SUMO tag

This recombinant protein can be used for biological assays. For research use only.