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Human recombinant sulphotransferase 1A1 (from E. coli)
Human recombinant sulphotransferase 1A1 (from E. coli)
Catalog # PRSI92-136
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant sulphotransferase 1A1 (from E. coli)
Catalog # PRSI92-136
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    N-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Sulfotransferase 1A1
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    35.5 kD
  • Sequence:
    Met1-Leu295
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris, 150 mM NaCl,1 mM EDTA,pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver, lung, adrenal, brain, platelets, and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilises 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyse the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Fusion-Tag: N-6 His tag

This recombinant protein can be used for biological assays. For research use only.