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Human recombinant Cystathionine Gamma-Lyase (from E. coli)
Catalog # PRSI92-113
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Cystathionine Gamma-Lyase (from E. coli)
Catalog # PRSI92-113
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Cystathionine Gamma-Lyase
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    44.7 kD
  • Sequence:
    Met1-Ser405
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl, 20% glycerol,pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyses the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterised by abnormal accumulation of plasma cystathionine.

This recombinant protein can be used for biological assays. For research use only.