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Human recombinant Bisphosphoglycerate Mutase (from E. coli)
Human recombinant Bisphosphoglycerate Mutase (from E. coli)
Catalog # PRSI92-092
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Bisphosphoglycerate Mutase (from E. coli)
Catalog # PRSI92-092
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Bisphosphoglycerate Mutase
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    31 kD
  • Sequence:
    Ser2-Lys259
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0 . Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Bisphosphoglycerate Mutase (BPGM) is a member of the Phosphoglycerate Mutase family and BPG-Dependent PGAM subfamily. BPGM is a multifunctional enzyme. BPGM catalyses 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. It also has phosphoglycerate phosphomutase activity. BPGM plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Deficiency of BPGM increases the affinity of cells for oxygen and result in hemolytic anemia.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.