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Mouse recombinant proprotein convertase 9
Mouse recombinant proprotein convertase 9
Catalog # PRSI91-783
Supplier:  ProSci Inc.
CAS Number:  
Mouse recombinant proprotein convertase 9
Catalog # PRSI91-783
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Species:
    Mouse
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Proprotein Convertase 9
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    74.8 kD
  • Sequence:
    Gln35-Gln692
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 50 mM HEPES, 150 mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesised as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.