Mouse recombinant proprotein convertase 9
Catalog # PRSI91-783
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Enzyme type:Recombinant
- Species:Mouse
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:Proprotein Convertase 9
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:74.8 kD
- Sequence:Gln35-Gln692
- Formulation:Supplied as a 0.2 µm filtered solution of 50 mM HEPES, 150 mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesised as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.