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Human recombinant Aldo-Keto Reductase 1C3 (from cells)
Human recombinant Aldo-Keto Reductase 1C3 (from cells)
Catalog # PRSI91-710
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Aldo-Keto Reductase 1C3 (from cells)
Catalog # PRSI91-710
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at –20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4...7 °C for 2 - 7 days. Aliquots of reconstituted samples are stable at –20 °C for 3 months.
  • Enzyme name:
    Aldo-Keto Reductase 1C3
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    37.8 kD
  • Sequence:
    Met1-Tyr323
  • Formulation:
    Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 150 mM NaCl,pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyses the conversion of aldehydes and ketones to alcohols. It catalyses the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. It can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.