Human recombinant tryptase beta-2 (from cells)
Catalog # PRSI91-456
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Enzyme type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:Tryptase beta-2
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:29.64 kD
- Sequence:Ala19-Pro275
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:For Biological Assays
Specifications
About this item
Tryptases are Trypsin-like Serine Proteases. beta -Tryptases are the main isoenzymes in mast cells. beta tryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, beta -Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, beta -Tryptases are released and participate in provoking inflammatory conditions . beta -Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.