Human recombinant Arylsulfatase A (from Cells)

PRSI91-281

PRSI91-281

Pk:
50 µG
Enzyme type:
Recombinant
Source:
Cells
Species:
Human
Tag sequence:
C-6 His tag
Storage conditions:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
Enzyme name:
Arylsulfatase A
Purity:
>95% as determined by reducing SDS-PAGE
Molecular weight:
52.9 kD
Sequence:
Arg19-Ala507
Formulation:
Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.