Human recombinant Aldo-Keto Reductase 1C3 (from E. coli)
PRSI91-275
:
- Pk:50 µG
- Enzyme type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:Aldo-Keto Reductase 1C3
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:36.74 kD
- Sequence:Met1-Tyr323
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5- alpha/5- beta -Steroid Reductases to convert Steroid hormones into the 3- alpha/5- alpha and 3- alpha/5- beta -Tetrahydrosteroids. AKR1C2 catalyses the inactivation of the most potent androgen 5- alpha-Dihydrotestosterone (5- alpha-DHT) to 5- alpha-Androstane-3- alpha, 17- beta -diol (3- alpha-diol).
This recombinant protein can be used for biological assays. For research use only.