Specifications

Pk:
50 µG
Enzyme type:
Recombinant
Source:
E. coli
Species:
Human
Tag sequence:
N-6 His tag
Storage conditions:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
Enzyme name:
PPIase
Purity:
>95% as determined by reducing SDS-PAGE
Molecular weight:
20.4 kD
Sequence:
Met1-Gly166
Formulation:
Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Specifications

About this item

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerisaion of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Fusion-Tag: N-6 His tag

This recombinant protein can be used for biological assays. For research use only.