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Human recombinant fumarase (from E. coli)
Human recombinant fumarase (from E. coli)
Catalog # PRSI91-204
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant fumarase (from E. coli)
Catalog # PRSI91-204
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Fumarase
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    50.2 kD
  • Sequence:
    Ala45-Lys510
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM Tris, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumour suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.

This recombinant protein can be used for biological assays. For research use only.