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Human recombinant TRIM5 (from E. coli)
Human recombinant TRIM5 (from E. coli)
Catalog # PRSI92-254
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant TRIM5 (from E. coli)
Catalog # PRSI92-254
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Environmentally Preferable:
  • Tag sequence:
    N-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
  • Protein synonyms:
    Tripartite motif-containing protein 5|RNF88|TRIM5|RING finger protein 88
  • Protein/peptide name:
    TRIM5
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    30.8 kD
  • Sequence:
    Met1-Gln248
  • Formulation:
    Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognises motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation

Fusion-Tag: N-6 His tag

This recombinant protein can be used for biological assays. For research use only.