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Human recombinant integrin alpha 5 (from cells)
Human recombinant integrin alpha 5 (from cells)
Catalog # PRSI91-433
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant integrin alpha 5 (from cells)
Catalog # PRSI91-433
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    FNRA|CD49e|Integrin Alpha-5|ITGA5|Fibronectin Receptor Subunit Alpha|VLA-5|Integrin Alpha-F|CD49 Antigen-like Family Member E
  • Protein/peptide name:
    Integrin alpha 5
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    105.11 kD
  • Sequence:
    Phe42-Tyr995
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    For Biological Assays

Specifications

About this item

Integrin alpha-5 belongs to the Integrin alpha chain family and contains 7 FG-GAP repeats. Integrin alpha-5 joins with Integrin- beta 1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin alpha-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag