Specifications
- Antigen name:Tumor Necrosis Factor Receptor Superfamily Member 11B
- Antigen symbol:TNFRSF11B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Reactivity:Human
- Western blot:Yes
- Form:Lyophilized
- Antigen synonyms:osteoprotegerin|osteoclastogenesis inhibitory factor|OCIF|TR1|tumor necrosis factor receptor superfamily member 11B|PDB5
- Immunogen:Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hOPG (human Osteoprotegrin).
- Size:100 µg
- Pk:100 µG
Specifications
About this item
Osteoprotegerin (OPG) is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of the gene have been reported, but their full length nature has not been determined.
Anti-hOPG specific antibody was purified by affinity chromatography employing immobilized hOPG matrix.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: TNFRSF11B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human