Specifications
- Antigen-Name:Sodium-hydrogen Antiporter 1
- Antigen-Symbol:NHE1
- Klonalität:Polyklonal
- Konjugation:Unconjugated
- ELISA:Yes
- Wirt:Rabbit
- ImmunoChemie:Yes
- ImmunFluoreszenz:Yes
- Isotyp:IgG
- Reaktivität:Human,Rat,Mouse
- Western blot:Yes
- Antigen-Synonyme:NHE-1|PPP1R143|SLC9A1|Sodiumûhydrogen antiporter 1|APNH|solute carrier family 9 member A1|NHE1|LIKNS
- Lagerungspuffer:PBS containing 0.02% sodium azide
- Immunogen:Nhe-1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human Nhe-1.
- Validierte Anwendungen:E, WB, IHC, IF
- Reinigung:Affinity chromatography purified via peptide column
- Größe:100 µg
- VE:100 µG
Specifications
About this item
Nhe-1 Antibody: The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.
Type:
Antigen: NHE-1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat