Order Entry
Switzerland
ContactUsLinkComponent
Anti-TRIM3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Anti-TRIM3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Catalog # BOSSBS-9174R-A555
Supplier:  Bioss
Anti-TRIM3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Catalog # BOSSBS-9174R-A555
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Tripartite Motif-containing 3
  • Antigen symbol:
    TRIM3
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 555
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Environmentally Preferable:
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    10612
  • Antigen synonyms:
    σ-actinin-4 interacts with the RBCC domain of TRIM3|also known as RING finger protein 22 RNF22|RING finger protein 97 RNF97 or brain-expressed RING finger protein BERP|two proteins associated with the actin cytoskeleton. Specically|also known as the RING-B-box coiled-coil RBCC family. Members of the RBCC family have an N-terminal RING finger|RNF9,Tripartite mot-containing protein 3 TRIM3|TRIM3 has been shown to interact with σ-actinin-4 and myosin V|a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments|followed by one or two zinc-binding domains B-box domains|is a 744 amino acid member of the TRIM family|and the C-terminal tail of Myosin V interacts with with the unique C-terminal Γê½-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Storage temperature:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Shipping temperature:
    4°C
  • Purification:
    Purified by Protein A
  • Pk:
    100 µl

Specifications

About this item

Tripartite motif-containing protein 3 (TRIM3), also known as RING finger protein 22 (RNF22), RING finger protein 97 (RNF97) or brain-expressed RING finger protein (BERP), is a 744 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Localized to cytoplasmic filaments, TRIM3 has been shown to interact with å-actinin-4 and myosin V, two proteins associated with the actin cytoskeleton. Specifically, å-actinin-4 interacts with the RBCC domain of TRIM3, and the C-terminal tail of Myosin V interacts with with the unique C-terminal ∫-propeller domain of TRIM3. These associations suggest that TRIM3 may play a role in cell motility and cargo transport. Three named isoforms of TRIM3 exist as a result of alternative splicing events.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TRIM3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat