Specifications
- Antikörper-Typ:Primär
- Antigen-Name:Potassium Voltage-gated Channel KQT-like Subfamily Member 1
- Antigen-Symbol:KCNQ1
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 350
- Wirt:Rabbit
- ImmunoChemie:Yes
- Isotyp:IgG
- Reaktivität:Human,Dog,Rat,Mouse
- Kreuzadsorption:No
- Form:liquid
- Gen-ID:3784
- Antigen-Synonyme:Kv7.1|JLNS1|FLJ26167|KCNQ1|potassium voltage-gated channel|Jervell and Lange-Nielsen syndrome 1|WRS|ATFB1|long (electrocardiographic) QT syndrome|SQT2|Ward-Romano syndrome 1|LQT1|LQT|KQT-like subfamily|Kv1.9|member 1|KCNA8|slow delayed rectifier channel subunit|KVLQT1|kidney and cardiac voltage dependend K+ channel|RWS|KCNA9
- Lagerungspuffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Lagertemperatur:Store at 4°C for 12 months
- Konzentration:1 μg/μl
- Transporttemperatur:4°C
- Immunogen:500-550/676
- Reinigung:Purified by Protein A
- VE:100 µl
Specifications
About this item
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: KCNQ1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Dog