- Antikörper-Typ:Primär
- Antigen-Name:Ectonucleoside triphosphate diphosphohydrolase 5
- Antigen-Symbol:ENTPD5
- Klonalität:Polyklonal
- Konjugation:Alexa Fluor® 647
- Wirt:Rabbit
- ImmunoChemie:Yes
- Isotyp:IgG
- Reaktivität:Human,Rat,Mouse
- Kreuzadsorption:No
- Form:liquid
- Gen-ID:957
- Antigen-Synonyme:PCPH|CD39L4|NTPDase-5
- Lagerungspuffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Lagertemperatur:Store at 4°C for 12 months
- Konzentration:1 μg/μl
- Transporttemperatur:4°C
- Immunogen:331-380/428
- Reinigung:Purified by Protein A
- VE:100 µl
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ENTPD5
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat