Rat CNTF ELISA Kit is used for detection of rat CNTF in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations.

CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.