- Antibody type:Primary
- Antigen name:cyclin-dependent kinase 5
- Antigen symbol:CDK5
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:none
- Gene ID:1020
- Antigen synonyms:PSSALRE|LIS7
- Storage temperature:Store for 1 year at –20 °C from date of shipment
- Shipping temperature:Ice
- Immunogen:His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells
- Purification:purified from Baculovirus expressed insect cells
- Size:100 µl
- Pk:0,1 mL
Cyclin-dependent kinase-5(CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons.
Western Blot: 1:500~1,000;
Type: Primary
Antigen: CDK5 (cyclin-dependent kinase 5)
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat