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Anti-Keratan Sulfate Rabbit Polyclonal Antibody
  BOSSBS-4894R
 :  Bioss
Anti-Keratan Sulfate Rabbit Polyclonal Antibody
  BOSSBS-4894R
 :  Bioss

 

  • Antibody type:
    Primary
  • Antigen name:
    Keratan Sulfate
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Form:
    liquid
  • Antigen synonyms:
    Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1|EC 2.8.2.21|Carbohydrate Chondroitin 6 keratan sulfotransferase 1|KSGAL6ST|Carbohydrate keratan sulfate Gal 6 sulfotransferase|CHST1|GST 1 Keratan sulfate Gal 6 sulfotransferase|KS6ST|Carbohydrate Chondroitin 6 keratan sulfotransferase|Carbohydrate sulfotransferase 1|KSST.|Carbohydrate keratan sulfate Gal 6 sulfotransferase 1
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
  • Concentration:
    1 ug/ul
  • Shipping temperature:
    4 °C
  • Purification:
    Purified by Protein A.
  • Size:
    100 μg
  • Pk:
    100 µl

 

 

Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Type: Primary
Antigen: Keratan Sulfate
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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