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Anti-CASK Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-CASK Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-11338R-A750
Supplier:  Bioss
Anti-CASK Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-11338R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    CASK
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat
  • Epitope:
    651-750/926
  • Form:
    Liquid
  • Antigen synonyms:
    Protein lin-2 homolog|CMG|Lin 2 homolog|Pals3|TNRC8|hCASK|LIN2 antibody Lin2 homolog|CAMGUK, drosophila, homolog of antibody casK|Calcium/calmodulin dependent serine protein kinase MAGUK family|Vertebtate LIN2 homolog|CAGH39|FGS4|Calcium/calmodulin-dependent serine protein kinase|Caki|Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase|Calcium/calmodulin dependent serine protein kinase|DXPri1|Trinucleotide repeat containing 8|CSKP_HUMAN|Peripheral plasma membrane protein CASK|LIN 2|MICPCH|MRXSNA|CAMGUK protein|DXRib1|CAMGUK
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    140 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human CASK
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumour suppression, and Signalling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterised by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in Signalling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

Type: Primary
Antigen: CASK
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 651-750/926
Host: Rabbit
Isotype: IgG
Reactivity: Rat

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