"chromatography caps"

Supplier: ProSci Inc.

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes.

Supplier: ProSci Inc.

DCP2 is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. It has higher activity towards mRNAs that lack a poly (A) tail, but has no activity towards a cap structure lacking a RNA moiety.DCP2 is a key component of an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).

Supplier: HICHROM

CIMmultus™ columns are based on an innovative monolithic technology. Distinguished by large pores/flow through channels these columns are designed for the production, purification, and analytics of large proteins (IgG, IgM, PEGylated proteins), viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), VLPs, exosomes and pDNA for example.

Supplier: Cytiva

HiLoad™ Superdex™ prep grade (pg) sind vorgepackte XK Säulen für die präparative Gelfiltration. Superdex™ prep grade ist eine Kompositmatrix aus Dextran und stark quervernetzter Agarose. Die steile Selektivität von Dextran und die hohe chemische und physikalische Stabilität von Agarose ermöglichen hochauflösende Trennungen. Das Chromatographiemedium verbindet hohe mechanische Festigkeit mit hoher Hydrophilie und ermöglicht hohe Flussraten und minimale nicht-spezifische Wechselwirkungen.

Supplier: VWR Collection

Vials, 1,5 ml PP, with 9 mm short thread cap, silicone/polypropylene.

Supplier: AGILENT HEWLETT PACKARD

All the parts required to connect solvent bottles to your HPLC instrument.

Supplier: Thermo Fisher Scientific

Die QuEChERS-Methode (schnell, einfach, kostengünstig, effektiv, robust und sicher) wird zunehmend die Methode der Wahl zur Extraktion von Pestizidrückständen in Obst, Gemüse und anderen Lebensmitteln. Die QuEChERS-Methode bietet den Vorteil hoher Rückgewinnung, genauer Ergebnisse und eines hohen Probendurchsatzes in Kombination mit Kosteneinsparungen durch geringen Lösungsmittelverbrauchs und niedrigen Anforderungen an den Arbeitsaufwand. Dennoch ist das Verfahren robust.

Supplier: ProSci Inc.

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Supplier: ProSci Inc.

PARN is an oligomeric, processive, and cap-interacting 3' exonuclease.

Supplier: Thermo Fisher Scientific

The Melon™ gel chromatography cartridge is a convenient, ready to use prepacked chromatography column for the isolation and purification of antibodies.

Supplier: Thermo Fisher Scientific

Pierce™ Protein G chromatography cartridges are convenient, ready to use prepacked devices for isolation and purification of mammalian polyclonal and monoclonal antibodies from serum, ascites and cell culture supernatants.

Supplier: ProSci Inc.

CAPS is a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit.This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants.

Supplier: AGILENT HEWLETT PACKARD

Stufe 2: Dispersive SPE-ReinigungWählen Sie das zerstreuend SPE-Kit, das für die Art der zu analysierenden Lebensmittel und die von Ihnen angewandte Methode geeignet ist. In diesem Schritt wird ein Aliquot des Probenextrakts aus Schritt eins (siehe QuEChERS-Extraktionskits) in ein 2- oder 15-ml-Zentrifugenröhrchen gegeben, das eine kleine Menge SPE-Sorbens und MgSO₄ enthält. Das Sorbens zieht störende Matrixmaterialien aus der Probe heraus, während das MgSO₄ dabei hilft, überschüssiges Wasser zu entfernen und die Analytverteilung zu verbessern.

Supplier: Thermo Fisher Scientific

Pierce™ Protein A chromatography cartridges are convenient, ready to use pre-packed devices for the isolation and purification of polyclonal and monoclonal antibodies. These cartridges are effective for routine affinity purification of polyclonal and monoclonal IgG from serum, ascites and cell culture supernatant.

Supplier: VARIAN

Bond Elut™ Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with non-polar C8 and strong anion exchange (SAX) sorbent. It has been optimised for acidic drugs such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen and other compounds that possess both non-polar and anionic characteristics.

Supplier: ProSci Inc.

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.