"Cayman Chemical"

CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively, versus IC50 = 25 μM for NMDA receptors).
This compound has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors.

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Anti-TRF2 Goat Polyclonal Antibody

Supplier: Cayman Chemical

Anti-TRF2 Goat Polyclonal Antibody

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Hydroxy-2-naphthalenylmethylphosphonic acid ≥95%, kristalliner Feststoff

Supplier: Cayman Chemical

HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity.

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7-Bromisochinolin

Supplier: Cayman Chemical

7-Bromisochinolin

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Nortriptylin -hydrochlorid ≥98%, kristalliner Feststoff

Supplier: Cayman Chemical

Nortriptyline is a tricyclic antidepressant that blocks norepinephrine and serotonin transporters (K_Ds = 4.4 and 18 nM, respectively) more potently than the dopamine transporter (K_D = 1.1 µM). It also antagonises serotonin, histamine, muscarinic, and α-adrenergic receptors (K_is = 5.0, 8.5, 10, 40, and 60 nM for 5-HT_2A, 5-HT_2C, H₁, α₁, and M₁ receptors, respectively).

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N-Octyl-β-D-glucopyranosid

Supplier: Cayman Chemical

N-Octyl-β-D-glucopyranosid

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4-Phenyl-1,2,3-thiadiazol ≥98%

Supplier: Cayman Chemical

Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolises substituted amines, CYP2E1 metabolises various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 µM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner.

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Anti-NR2B subunit of NMDA Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-NR2B subunit of NMDA Rabbit Polyclonal Antibody

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Anti-CD144 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-CD144 Rabbit Polyclonal Antibody

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Purvalanol A ≥98%, kristalliner Feststoff

Supplier: Cayman Chemical

Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.