This nucleotide consists of a modified base, a ribose, and a 5′ triphosphate group.

• Can be incorporated in in vitro transcription for modification of synthesised RNA for desired characteristics
• ≥95% purity by AX-HPLC analysis, provided as 100 mM in H₂O
• Grade: RUO

Methylation of the 5 position of cytidine is a common, post-transcriptional modification in a number of RNA species, such as mRNA, miRNA and tRNA. 5-Methylcytidine-5'-Triphosphate (5-Methyl-CTP) is a modified nucleoside triphosphate employed to impart desirable characteristics such as increased nuclease stability, increased translation or reduced interaction of innate immune receptors with in vitro transcribed RNA.