IL-15 is a widely expressed proinflammatory cytokine that is structurally and functionally related to IL-2.

• High quality
• Low endotoxin
• Lot-to-lot consistency
• Animal free
• Manufactured following GMP guidelines

Signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors
Regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function
Dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases
Combines with other common γ chain cytokines (IL-2, IL-7 and IL-21) to promote favorable anti-tumoral phenotypes in adoptive cellular therapies such as CAR-T cell therapy
The biological activity of CTGrade GMP interleukins and growth factors is standardised, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance

Host Cell Protein: ≤30 ng/ml
Host Cell DNA: ≤0,01 ng/ml
Sterility testing: No Growth
Mycoplasma: Negative