Mouse Recombinant IL-17A (Animal free) (from E. coli)

New Product

Mouse Recombinant IL-17A (Animal free) (from E. coli)

New Product

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

High Quality
Low Endotoxin
Affordable

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Mouse
Lagerbedingungen:
–20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0,1
Biologische Aktivität:
Bioactivity assay: Production of IL-6 by mouse 3T3 cells, ED50 ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
Gen-ID:
Q62386
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
Y
Proteinsynonym:
IL-17|CTLA-8
Protein/Peptid-Name:
IL-17A
Purity:
≥95%
Molecular weight:
15,1/30,2 kDa
Sequence:
MAAIIPQSSA CPNTEAKDFL QNVKVNLKVF NSLGAKVSSR RPSDYLNRST SPWTLHRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPESCPF TFRVEKMLVG VGCTCVASIV RQAA
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic Acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay