CD9 (Mouse) Flow Antibody is validated by Biotium for detection of mouse CD9 EV marker in isolated EVs. The antibody conjugates offer exceptional signal-to-noise and include color options for the Pacific Blue™, FITC, PE, and APC channels.

• Optimal detection of mouse CD9 EV marker by flow cytometry
• Validated for purified or bead-bound EVs
• Bright signal and low background
• Available in 4 colours

Extracellular vesicles (EVs), including exosomes, are lipid-bound vesicles that are released from cells. EVs display specific surface proteins and can carry nucleic acids and other cargo, allowing them to transfer biological information between cells in different parts of the body.

Therefore EVs are increasingly studied for their potential use in drug delivery and medical diagnostic applications. The most common proteins used as EV markers are CD9, CD63, and CD81, members of the tetraspanin family. Tetraspanins are plasma membrane proteins with many proposed functions, including activation and sorting of other membrane proteins.

They are also thought to play a role in the targeting of proteins to multivesicular bodies (MVBs) and exosomes. These tetraspanins are broadly expressed on many cell types and can therefore be detected on many types of EVs, but their expression levels vary depending on the cell type of origin.

Type: Primary
Antigen: CD9
Clonality: Monoclonal
Clone:
Conjugation: ExoBrite™ 410/450
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse