Mouse Recombinant IGF-II (Animal free) (from E. coli)

Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death.

High quality
Low endotoxin
Affordable

IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

: Certificate of Analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.

: For research use only.

Konjugation:
Unconjugated
Protein-Funktion:
Cytokine
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Mouse
Lagerbedingungen:
−20 °C
Endotoxingehalt:
Endotoxin LAL (EU/µg) ≤0.1
Biologische Aktivität:
Bioactivity assay: FDC-P1 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Gen-ID:
P09535
Reconstitution instructions:
Sterile water at 0,1 mg/ml
Frei von Endotoxinen:
N
Frei von Trägern:
Y
Frei von Proteasen:
N
Tierfrei:
Y
Proteinsynonym:
Somatomedin A
UniProtKB:
P09535
Protein/Peptid-Name:
IGF-II
Purity:
≥95%
Molecular weight:
7,4 kDa
Sequence:
AYGPGETLCG GELVDTLQFV CSDRGFYFSR PSSRANRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Endotoxinspiegel:
Low
Zusammensetzung:
0,1% Trifluoroacetic Acid (TFA)
Frei von Nukleasen:
N
Sorte:
RUO
Transporttemperatur:
RT
Validierte Anwendungen:
Bioassay