Mouse Recombinant IGF-II (Animal free) (from E. coli)
Supplier: Shenandoah Biotechnology
Certificates
About this item
Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death.
- High quality
- Low endotoxin
- Affordable
IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.
Delivery: Certificate of Analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Mouse
- Lagerbedingungen:−20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0.1
- Biologische Aktivität:Bioactivity assay: FDC-P1 cell proliferation, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
- Gen-ID:P09535
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:Y
- Proteinsynonym:Somatomedin A
- UniProtKB:P09535
- Protein/Peptid-Name:IGF-II
- Purity:≥95%
- Molecular weight:7,4 kDa
- Sequence:AYGPGETLCG GELVDTLQFV CSDRGFYFSR PSSRANRRSR GIVEECCFRS CDLALLETYC ATPAKSE
- Endotoxinspiegel:Low
- Zusammensetzung:0,1% Trifluoroacetic Acid (TFA)
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
- Validierte Anwendungen:Bioassay
Specifications
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