Human recombinant FGF21 (from E. coli)
Anbieter: Shenandoah Biotechnology
Zertifikate
Über diesen Artikel
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
Delivery: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Technische Daten
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Gen-ID:Q9NSA1
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:Y
- Proteinsynonym:Fibroblast Growth Factor-21|FGF-21|FGFL
- Protein/Peptid-Name:FGF21
- Purity:≥95%
- Molecular weight:19,5 kDa
- Sequence:MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Endotoxinspiegel:Low
- Zusammensetzung:10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
- Validierte Anwendungen:Bioassay
- Aminosäurezahl:182
Technische Daten
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