Human recombinant FGF21 (from E. coli)
Über diesen Artikel
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
: This product is for research use only and is not for use in humans.
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Product Details & Documents
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
: This product is for research use only and is not for use in humans.
Spezifikationen für diese Produktfamilie
Technische Daten
Technische Daten
- Catalog No:
- SHBT100-148AF-5UG
- SHBT100-148AF-20UG
- SHBT100-148AF100UG
- SHBT100-148AF500UG
- SHBT100-148AF-1MG
- Protein/Peptid-Name:
- FGF21
- FGF21
- FGF-21
- FGF-21
- FGF21
- Proteinsynonym:
- Fibroblast Growth Factor-21|FGF-21|FGFL
- Fibroblast Growth Factor-21|FGF-21|FGFL
- FGFL
- FGFL
- Fibroblast Growth Factor-21|FGF-21|FGFL
- Protein/Peptid-Typ:
- Rekombinant
- Rekombinant
- Rekombinant
- Rekombinant
- Rekombinant
- Protein-Funktion:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Spezies:
- Human
- Human
- Human
- Human
- Human
- Ursprung:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Konjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gen-ID:
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Sequence:
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Aminosäurezahl:
- 182
- 182
- Frei von Proteasen:
- N
- N
- N
- N
- N
- Tierfrei:
- Y
- Y
- Y
- Y
- Y
- Frei von Nukleasen:
- N
- N
- N
- N
- N
- Frei von Trägern:
- Y
- Y
- Y
- Y
- Y
- Frei von Endotoxinen:
- N
- N
- N
- N
- N
- Endotoxinspiegel:
- Low
- Low
- Low
- Low
- Low
- Endotoxingehalt:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Sorte:
- RUO
- RUO
- RUO
- RUO
- RUO
- Zusammensetzung:
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- Molekulargewicht:
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- Reconstitution instructions:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Lagerbedingungen:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Transporttemperatur:
- RT
- RT
- RT
- RT
- RT
- Validierte Anwendungen:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Technische Daten
Product Family Options
Produktinformationen
- PackungVEVerfügbarkeitPreis
- Spezifikationen:
Mehr
Specifications
Cat. No.SHBT100-148AF-5UGProtein/Peptid-NameFGF21ProteinsynonymFibroblast Growth Factor-21|FGF-21|FGFLProtein/Peptid-TypRekombinantProtein-FunktionCytokineSpeziesHumanUrsprungE. coliKonjugationUnconjugatedGen-IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAminosäurezahlFrei von ProteasenNTierfreiYFrei von NukleasenNFrei von TrägernYFrei von EndotoxinenNEndotoxinspiegelLowEndotoxingehaltEndotoxin LAL (EU/µg) ≤0,1Biologische AktivitätBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%SorteRUOZusammensetzung10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molekulargewicht19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlLagerbedingungen–20 °CTransporttemperaturRTValidierte AnwendungenBioassay - Spezifikationen:
Mehr
Specifications
Cat. No.SHBT100-148AF-20UGProtein/Peptid-NameFGF21ProteinsynonymFibroblast Growth Factor-21|FGF-21|FGFLProtein/Peptid-TypRekombinantProtein-FunktionCytokineSpeziesHumanUrsprungE. coliKonjugationUnconjugatedGen-IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAminosäurezahlFrei von ProteasenNTierfreiYFrei von NukleasenNFrei von TrägernYFrei von EndotoxinenNEndotoxinspiegelLowEndotoxingehaltEndotoxin LAL (EU/µg) ≤0,1Biologische AktivitätBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%SorteRUOZusammensetzung10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molekulargewicht19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlLagerbedingungen–20 °CTransporttemperaturRTValidierte AnwendungenBioassay - Spezifikationen:
Mehr
Specifications
Cat. No.SHBT100-148AF100UGProtein/Peptid-NameFGF-21ProteinsynonymFGFLProtein/Peptid-TypRekombinantProtein-FunktionCytokineSpeziesHumanUrsprungE. coliKonjugationUnconjugatedGen-IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAminosäurezahl182Frei von ProteasenNTierfreiYFrei von NukleasenNFrei von TrägernYFrei von EndotoxinenNEndotoxinspiegelLowEndotoxingehaltEndotoxin LAL (EU/µg) ≤0,1Biologische AktivitätBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%SorteRUOZusammensetzung10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molekulargewicht19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlLagerbedingungen–20 °CTransporttemperaturRTValidierte AnwendungenBioassay - Spezifikationen:
Mehr
Specifications
Cat. No.SHBT100-148AF500UGProtein/Peptid-NameFGF-21ProteinsynonymFGFLProtein/Peptid-TypRekombinantProtein-FunktionCytokineSpeziesHumanUrsprungE. coliKonjugationUnconjugatedGen-IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAminosäurezahl182Frei von ProteasenNTierfreiYFrei von NukleasenNFrei von TrägernYFrei von EndotoxinenNEndotoxinspiegelLowEndotoxingehaltEndotoxin LAL (EU/µg) ≤0,1Biologische AktivitätBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%SorteRUOZusammensetzung10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molekulargewicht19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlLagerbedingungen–20 °CTransporttemperaturRTValidierte AnwendungenBioassay - Spezifikationen:
Mehr
Specifications
Cat. No.SHBT100-148AF-1MGProtein/Peptid-NameFGF21ProteinsynonymFibroblast Growth Factor-21|FGF-21|FGFLProtein/Peptid-TypRekombinantProtein-FunktionCytokineSpeziesHumanUrsprungE. coliKonjugationUnconjugatedGen-IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAminosäurezahlFrei von ProteasenNTierfreiYFrei von NukleasenNFrei von TrägernYFrei von EndotoxinenNEndotoxinspiegelLowEndotoxingehaltEndotoxin LAL (EU/µg) ≤0,1Biologische AktivitätBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%SorteRUOZusammensetzung10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molekulargewicht19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlLagerbedingungen–20 °CTransporttemperaturRTValidierte AnwendungenBioassay
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