Pro-DeliverIN CRISPR is a transfection reagent optimised for recombinant Cas9 protein delivery or Cas9/gRNA RNP complexes. Suitable for gene editing applications, this reagent provides high transfection efficiency with minimal toxicity.

• High efficiency delivery of Cas9 protein or Cas9 gRNA complexes
• Low cell toxicity - enable to start experiment with less cells

The Cas 9 recombinant protein is delivered more rapidly than nucleic acid and is fully active once inside the cells without latency period (in contrast to transcription and translation machineries required for the nucleic acids). As for mRNA, it also offers the advantage of avoiding genomic integration and is cell cycle independent.

Efficient delivery represents a critical step for genome editing experiments.