Human Recombinant PTN (from E. coli)
Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis.
- High quality
- Low endotoxin
- Affordable
PTN binds with low affinity to the cell surface receptor nucleolin to inhibit HIV-1 infection. PNT also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.
It is also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.
: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
: For research use only.
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Lagerbedingungen:−20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0.1
- Biologische Aktivität:Bioactivity: No biological activity data is available at this time
- Gen-ID:P21246
- Reconstitution instructions:Sterile water at 0,1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Proteinsynonym:NEGF1|HARP|HBBM|HBGF-8
- UniProtKB:P21246
- Protein/Peptid-Name:Pleiotrophin
- Purity:≥95%
- Molecular weight:15,4 kDa
- Sequence:MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRTGS LKRALHNAEC QKTVTISKPC GKLTKPKPQA ESKKKKKEGK KQEKMLD
- Endotoxinspiegel:Low
- Zusammensetzung:10 mM sodium phosphate, pH 7,5
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
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