Human recombinant FGF-22 (from E. coli)
Fibroblast growth factor 22 (FGF-22) is a mediator of synaptogenesis in the adult nervous system and functions to regulate synapse formation and maturation.
- Produced from genetically modified E. coli
- Monomeric protein, containing 149 amino acids
It is expressed in the inner hair cell and functions to maintain ribbon synapse number to protect functional hearing. In the hippocampus, FGF-22 promotes excitatory synapse formation through binding the FGFR2b and FGFR1b receptors. FGF-22 is also required for axonal circuit remodeling after spinal cord injury.
: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
: This product is for research use only and is not for use in humans.
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Human
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity assay: Currently undetertmined, ED50 ≤Currenlty undetermined, Bioactivity ≥Currently undetermined
- Gen-ID:Q9HCT0
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Proteinsynonym:FGFM
- Protein/Peptid-Name:FGF-22
- Purity:≥95%
- Molecular weight:17,3 kDa
- Sequence:MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTVDCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS
- Endotoxinspiegel:Low
- Zusammensetzung:0,1% Trifluoroacetic Acid (TFA)
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
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