Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.
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A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.
- Konjugation:Unconjugated
- Protein-Funktion:Cytokine
- Protein/Peptid-Typ:Rekombinant
- Ursprung:E. coli
- Spezies:Mouse
- Lagerbedingungen:–20 °C
- Endotoxingehalt:Endotoxin LAL (EU/µg) ≤0,1
- Biologische Aktivität:Bioactivity assay: 2E8 cell proliferation, ED50 ≤1 ng/ml, Bioactivity ≥1,0×10⁶ units/mg
- Gen-ID:P10168
- Reconstitution instructions:Sterile 10 mM acetic acid at 0.1 mg/ml
- Frei von Endotoxinen:N
- Frei von Trägern:Y
- Frei von Proteasen:N
- Tierfrei:N
- Proteinsynonym:Lymphopoietin 1 (LP-1)|pre-B cell Factor
- Protein/Peptid-Name:IL-7
- Purity:≥95%
- Molecular weight:15 kDa
- Sequence:MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI
- Endotoxinspiegel:Low
- Zusammensetzung:0,1% Trifluoroacetic Acid (TFA)
- Frei von Nukleasen:N
- Sorte:RUO
- Transporttemperatur:RT
- Validierte Anwendungen:Bioassay