Affinity chromatography media, MabSelect™ PrismA

MabSelect™ PrismA has been improved with an optimised high-flow agarose base matrix and a genetically engineered protein A-derived ligand, allowing future demands in mAb processing to be met.

Enhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit
Excellent alkaline stability enables efficient cleaning and sanitisation using 0,5 to 1,0 M NaOH for improved process economy, bioburden, control and robustness
Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand

MabSelect™ PrismA builds on the proven track record of MabSelect™ and MabSelect™ SuRe™ resins in commercial mAb production.

MabSelect™ PrismA has been improved with an optimised high-flow agarose base matrix and a genetically engineered protein A-derived ligand, allowing future demands in mAb processing to be met.

Enhanced dynamic binding capacity allows high mass throughput of processed mAb per resin volume unit
Excellent alkaline stability enables efficient cleaning and sanitisation using 0,5 to 1,0 M NaOH for improved process economy, bioburden, control and robustness
Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand

MabSelect™ PrismA builds on the proven track record of MabSelect™ and MabSelect™ SuRe™ resins in commercial mAb production.

Catalog No:
17-5498-01
17-5498-02

Ligand:
Alkaline-stabilised protein A-derived (E.coli)
Alkaline-stabilised protein A-derived (E.coli)

Methode der Ligandenkupplung:
Epoxy
Epoxy

Matrix:
Rigid, highly cross-linked agarose
Rigid, highly cross-linked agarose

pH-Bereich:
3 – 12
3 – 12

Bindungskapazität:
~ 40 mg polyclonal IgG/ml resin, 2 min residence time
~ 80 mg polyclonal IgG/ml resin, 6 min residence time
~ 40 mg polyclonal IgG/ml resin, 2 min residence time
~ 80 mg polyclonal IgG/ml resin, 6 min residence time

Lagertemperatur:
2 - 8 °C
2 - 8 °C

Product Family Options

Bezeichnung
Typ
Partikelgröße
VE
17-5498-01
MabSelect™ PrismA
Liquid
60 µm
25 mL

1 * 25 mL
1 * 25 mL - 1 190.00 SFr.
1 190.00 SFr.
1 * 25 mL
1 190.00 SFr.

Specifications
Cat. No.
17-5498-01
Ligand
Alkaline-stabilised protein A-derived (E.coli)
Methode der Ligandenkupplung
Epoxy
Matrix
Rigid, highly cross-linked agarose
pH-Bereich
3 – 12
Bindungskapazität
~ 40 mg polyclonal IgG/ml resin, 2 min residence time
~ 80 mg polyclonal IgG/ml resin, 6 min residence time
Lagertemperatur
2 - 8 °C
17-5498-02
MabSelect™ PrismA
Liquid
60 µm
200 ml

1 * 200 mL
1 * 200 mL - 6 300.00 SFr.
6 300.00 SFr.
1 * 200 mL
6 300.00 SFr.

Specifications
Cat. No.
17-5498-02
Ligand
Alkaline-stabilised protein A-derived (E.coli)
Methode der Ligandenkupplung
Epoxy
Matrix
Rigid, highly cross-linked agarose
pH-Bereich
3 – 12
Bindungskapazität
~ 40 mg polyclonal IgG/ml resin, 2 min residence time
~ 80 mg polyclonal IgG/ml resin, 6 min residence time
Lagertemperatur
2 - 8 °C