Technische Daten

VE:
10 µG
Protein/Peptid-Typ:
Rekombinant
Ursprung:
CHO cells
Spezies:
Mouse
Seq:
02
Biologische Aktivität:
Binds to mouse and human CD40. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86).
Reconstitution instructions:
Reconstitute with 100 µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
Protein/Peptid-Name:
MegaCD40L™ (soluble)
Purity:
>95% (SDS-PAGE)
Konzentration:
0,1 mg/ml after reconstitution
Zusammensetzung:
Lyophilised. Contains PBS.

Technische Daten

Über diesen Artikel

Highly active

Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.

MegaCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30/adiponectin. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations (Prod. No. ALX-850-075).