Mouse recombinant MegaCD40L™ (soluble) (from CHO cells)
Product Details & Documents
Highly active
Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
MegaCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30/adiponectin. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L. It provides a simple and equally potent alternative to [CD40L+enhancer] combinations (Prod. No. ALX-850-075).
Technische Daten
Technische Daten
- VE:10 µG
- Zusammensetzung:Lyophilised. Contains PBS.
- Cat. No.:ENZOALX522120C010
- Ursprung:CHO cells
- Reconstitution instructions:Reconstitute with 100 µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
- Purity:>95% (SDS-PAGE)
- Spezies:Mouse
- Konzentration:0,1 mg/ml after reconstitution
- Protein/Peptid-Typ:Rekombinant
- Protein/Peptid-Name:MegaCD40L™ (soluble)
- Biologische Aktivität:Binds to mouse and human CD40. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86).
Technische Daten
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