Human recombinant partner of Y14 and mago (from E. coli)

PRSI91-994

PRSI91-994

VE:
50 µG
Protein/Peptid-Typ:
Rekombinant
Ursprung:
E. coli
Spezies:
Human
Tag sequence:
C-6 His tag
Lagerbedingungen:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Proteinsynonym:
Partner of Y14 and Mago|PYM|WIBG|Protein Wibg Homolog
Protein/Peptid-Name:
Partner of Y14 and Mago
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
23.7 kD
Sequence:
Met1-Leu204
Zusammensetzung:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Validierte Anwendungen:
Bioassay

Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partner of Mago-14, relates with Mago-14 by its N-terminal domain.

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag