Technische Daten
- VE:50 µG
- Protein/Peptid-Typ:Rekombinant
- Ursprung:Cells
- Spezies:Human
- Tag sequence:C-6 His tag
- Lagerbedingungen:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Proteinsynonym:Leukocyte Immunoglobulin-like Receptor Subfamily B Member 2|Leukocyte Immunoglobulin-like Receptor 2|MIR-10|CD85d|LIR-2|ILT4|Immunoglobulin-like Transcript 4|Monocyte/Macrophage Immunoglobulin-like Receptor 10|CD85 Antigen-like Family Member D|LILRB2|LIR2|ILT-4|MIR10
- Protein/Peptid-Name:LILRB2
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:48.57 kD
- Sequence:Gln22-His458
- Zusammensetzung:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Validierte Anwendungen:For Biological Assays
Technische Daten
Über diesen Artikel
Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag