Human IL6R alpha ELISA Kit for the quantitative detection of human Interleukin-6 receptor alpha.

• No detectable cross-reactivity with other relevant proteins

IL6R alpha IL6Rα also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL6 receptor subunit IL6R and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerisation status. IL6R dimerisation occurs both on the cell surface and in solution.