9652 Résultats pour : « Rockland Immunochemical »

Supplier: Rockland Immunochemical

Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP39 (Rho GTPase activating protein 39) is a 1, 083 amino acid nuclear protein that contains one MyTH4 domain, one Rho GAP domain and two WW domains. It is encoded by a gene located on human chromosome 8, which is associated with a variety of diseases and malignancies. ARHGAP39 regulates robo signaling and plays important roles in axon guidance.

Supplier: Rockland Immunochemical

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4). Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.

Supplier: Rockland Immunochemical

Humanized Recombinant Anti-Anti-TNFα Fab fragment Antibody has been tested for use in Western Blot and ELISA. This antibody recognizes structured TNFα and will work in western blot when the protein has not been denatured with DTT or bMe. Although not tested, this antibody could be useful in in IHC and in in-vivo and other cellular assays. Specific conditions for reactivity should be optimized by the end user.

Supplier: Rockland Immunochemical

Anti-Herpes Simplex Virus Type II (HSV2) (MOUSE) Monoclonal Antibody was tested with IHC-P positive control infected lung tissues. Cellular Localization: Cytoplasmic, nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.

Supplier: Rockland Immunochemical

POL II, Polyclonal antibody, Host: Rabbit, Species: Human, Isotype: IgG, Immunogen: shows 100% identity with mouse and Chinese hamster, Synonyms: RPO2, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, Size: 25 uL

Supplier: Rockland Immunochemical

RFP Min X Hu Ms and Rt Serum Proteins, ready to use, Polyclonal antibody, Host: Rabbit, Isotype: IgG, Immunogen: Red Fluorescent Protein (RFP) fusion protein corresponding to the full length amino acid sequence (234aa), Synonyms: DsRed protein, Size: 100ul

Supplier: Rockland Immunochemical

PDCD4, ready to use, Polyclonal antibody, Host: Rabbit, Species: Human, Cross Reactivity: mouse, rat, Xenopus, Isotype: IgG, Immunogen: synthetic peptide corresponding amino acids near the carboxyl terminus, Synonyms: Nuclear antigen H731, Size: 100ul

Supplier: Rockland Immunochemical

ATF6, Polyclonal antibody, Host: Rabbit, Species: Human, Isotype: IgG, Immunogen: shows 100% identity with human and 80% identity to rat, Synonyms: Cyclic AMP-dependent transcription factor ATF-6 alpha, Activating transcription factor 6 alpha, ATF6 a, Size: 25 uL

Supplier: Rockland Immunochemical

TrueBlot® Biotin Magnetic Beads

Supplier: Rockland Immunochemical

MEK1 C-Term Blocking Control Peptide

Supplier: Rockland Immunochemical

This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). ACSS2 (Acyl-CoA synthetase short-chain family member 2) is a protein coding gene encoding a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. This protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. This protein is upregulated in many cancers and is important for pro-survival under hypoxic conditions. ACSS2 may be associated with disorders such as Cystoisosporiasis. Anti-ACSS2 Antibody is useful for researchers interested in parasites, intestines, Glucose Energy Metabolism, and AKT research.

Supplier: Rockland Immunochemical

TAF10 (TATA-Box Binding Protein Associated Factor 10) is the protein that coordinates activities for the initiation of transcription by RNA polymerase II required for activities of more than 70 polypeptides. TFIID binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as co-activators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs. Anti-TAF10 Antibody is useful for researchers interested in Chromatin research, transcription factor activity research, and DNA binding and transcription co-activator activity research.

Supplier: Rockland Immunochemical

Anti-Collagen Type IV detects collagen. Type-IV collagen is a type of collagen found primarily in the basal lamina. It is the major structural element of basal membranes. Anti-Collagen Type IV antibody is ideal for investigators involved in Cell Signaling, Neuroscience and Signal Transduction research.

Supplier: Rockland Immunochemical

ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Supplier: Rockland Immunochemical

ERK1 antibodies detect the ERK1 isoform. Mitogen activiated protein kinase 3, also known as MAPK3, ERK, or ERK1, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Supplier: Rockland Immunochemical

Suspensions are suitable for complement fixation, hemagglutination, hemadsorption, and other related serological procedures

Supplier: Rockland Immunochemical

Antibody to PUMA (p53 Upregulated Modulator of Apoptosis) (Rabbit) tested by western & immunocytochemistry. K562 or 3T3 cell lysates can be used as positive controls in WB & a band at ~23 kDa can be detected. A lower band at ~16 kDa was detected in MOLT4 and U937 cell lysates, which may represent the PUMA-??form. Specific conditions for reactivity should be optimized by the end user.

Supplier: Rockland Immunochemical

This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 265 kDa in size corresponding to Rif1 by western blotting in the appropriate cell lysate.

Supplier: Rockland Immunochemical

This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band at ~29 kDa in size corresponding to PCNA by western blotting in the appropriate cell lysate.

Supplier: Rockland Immunochemical

This affinity purified antibody has been tested for use in ELISA, immunochemistry and western blot.  Specific conditions for reactivity should be optimized by the end user.Expect a band (maybe a doublet) ~35 kDa in size.

Supplier: Rockland Immunochemical

This affinity purified antibody has been tested for use in western blotting using HeLa nuclear extracts.  The antibody is also functional by ELISA.

Supplier: Rockland Immunochemical

Phosphoserine Antibody is suitable for use in ELISA, western blotting and immunoprecipitation assays.  The antibody reacts specifically with phosphoserine and shows minimal reactivity by ELISA and western blotting with Proteins containing phosphotyrosine.

Supplier: Rockland Immunochemical

HbA antibodies detect the hemoglobin beta subunit wild type variant A isoform. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA-2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. HbA antibody cross reacts with HbA-2 but does not react other forms Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.

Supplier: Rockland Immunochemical

Human PEDF - SerpinF1 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Rat KIM1 AccuSignal ELISA Kit

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Human BMP-7 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Human PECAM-1 - CD31 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

Mouse PECAM-1 - CD31 AccuSignal ELISA Kit

Supplier: Rockland Immunochemical

DyLight™ Multiplex 549/800 Duo Western Blot Kit

Supplier: Rockland Immunochemical

Human TSLP AccuSignal ELISA Kit