"Proteintech"

Supplier: Proteintech

DIDO1, also termed DATF-1, C20orf158, DATF1, KIAA0333 and DIO-1, is a putative transcription factor, weakly pro-apoptotic when overexpressed. It is a tumor suppressor. In mice, DIDO1 is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. The human DIDO1 is similar to the mouse gene and therefore is thought to be involved in apoptosis. The immunogen of this antibody is the C-terminal of isoform 2 of DATF1(DIDO1).

Supplier: Proteintech

Anti-PECR Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-303 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

The ZNF114 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZNF114. This antibody recognizes human, mouse antigen. The ZNF114 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The TRMT61B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TRMT61B. This antibody recognizes human antigen. The TRMT61B antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

The virul-induced expression of interferon(IFN) genes in infected cells implicate in the interplay of several constitutively expressed and virus-activated transcription factors. A family of IFN regulatory factors(IRFs) have been shown to has a role in the transcription of IFN genes as well as IFN-stimulated genes. IRF3 is a novel key transcriptional regulator of type I IFN-dependent immune responses and involves in the innate immune response against DNA and RNA viruses, by binding to the promoters of IFN. It located in the cytoplasm of uninfected cells in an inactive form, and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, could be phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes

Supplier: Proteintech

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box . It functions through recruitment of C-terminal binding proteins (CtBPs) and histone deacetylases (HDACs) to its N-terminal and central domains, respectively . It is a scaffold for both histone deacetylases (HDACs) and C-terminal binding protein (CtBP) corepressors and functions by both HDAC-dependent and -independent mechanisms in a receptor-specific manner.

Supplier: Proteintech

GAK(cyclin-G-associated kinase) belongs to the protein kinase superfamily. GAK plays a more positive role as a modulator of signal transduction, by relaying the phosphorylation signal from an unidentified tyrosine kinase to unidentified GAK phosphorylation targets. It may be acting as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by hsc70 in non-neuronal cells.

Supplier: Proteintech

The ARMETL1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ARMETL1. This antibody recognizes human antigen. The ARMETL1 antibody has been validated for the following applications: ELISA, IHC analysis.

Supplier: Proteintech

Anti-THEM2 Antibody, Host Species: Rabbit, Cross Reactivity: Human,Mouse,Rat, Immunogen: Recombinant Protein, 1-140 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, IHC, Recommended Storage: - 20 C or lower

Supplier: Proteintech

ATXN3, which has deubiquitinase activity and act as a component of the ubiquitin proteasome system, plays a role in transcriptional regulation and neuroprotection. ATXN3 interacts with RAD23, HHR23A and HHR23B, involves in the pathology of MJD. ATXN3 is a mixed-linkage, chain-editing enzyme and that the UIM region of ATXN3 regulates its substrate specificity. Contains an N-terminal deubiquitinating domain, called the Josephin domain, followed by 2 ubiquitin-interacting motifs (UIMs) and a polyQ tract near the C terminus. ATXN3 can be phosphorylated in a protein casein kinase-2-dependent manner, thus the MW would be larger than the predicted one.

Supplier: Proteintech

The DSN1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DSN1. This antibody recognizes human,mouse,rat antigen. The DSN1 antibody has been validated for the following applications: ELISA, WB analysis.

Supplier: Proteintech

ELAVL1, also named as HUR, belongs to the RRM elav family. It is involved in 3'-UTR ARE-mediated MYC stabilization. ELAVL1 binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, ELAVL1 binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.

Supplier: Proteintech

GK5(Putative glycerol kinase 5) is also named as ATP:glycerol 3-phosphotransferase 5 and belongs to the FGGY kinase family.It is involved in Glycerol metabolism and catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate.It has 3 isoforms produced by alternative splicing.

Supplier: Proteintech

Annexin IV /placental anticoagulant protein II (ANX4) is a member of the annexin or lipocortin family of calcium-dependent phospholipid binding proteins, and is located at 2p13. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 shares 45 to 59% identity with other members and possibly interacts with ATP. ANX4 has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.

Supplier: Proteintech

Anti-CNTD1 Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Fusion Protein, 203-330 amino acid, Format:Antigen affinity purification, Application: ELISA, WB, Recommended Storage: - 20 C or lower

Supplier: Proteintech

Anti-LACRT Antibody, Host Species: Rabbit, Cross Reactivity: Human, Immunogen: Recombinant Protein, 20-138 amino acid, Format:Antigen affinity purification, Application: ELISA, IHC, Recommended Storage: - 20 C or lower